Vladimir Badmaev, MD, PhD, CEO of American Medical Holdings, presented results of a newly published study in Nutrients, (2015, 7, 9508-9522) showing that Coleus forskohlli — a component used in the proprietary FB3 botanical weight management formula —may assist in weight management by improving parameters of metabolic health.
 
The randomized, double-blind placebo-controlled clinical study assessed the effects of 12 weeks supplementation with 250 mg per day of C. forskohlii on key markers of obesity and metabolic parameters in 30 overweight and obese individuals. All participants were advised to follow a hypocaloric diet throughout the study.
 
According to Dr. Badmaev, the major finding of the study was that supplementation with C. forskohlii extract in conjunction with a hypocaloric diet significantly improved insulin and insulin resistance and thus may be useful in the management of metabolic risk factors. The Coleus forskohlii receiving group, but not placebo group, showed a favorable improvement in insulin concentration and insulin resistance (p = 0.001; 0.01 respectively) compared to the placebo group. 
 
“Interestingly, the intakes of total energy, fat, saturated fat, carbohydrate and dietary cholesterol were significantly reduced in the Coleus forskohlii group and thus the present study indicates that supplementation with C. forskohlii extract in conjunction with dietary advice may be useful for reducing dietary intake,” he explained. 
 
Dr. Badmaev added that although it is not clear how C. forskohlii supplementation influences and diminishes dietary fat intake, emerging studies have shown that low fat taste sensitivity is associated with overweight and obesity. The authors of the current study hypothesize that in overweight and obese subjects C. forskohllii supplementation could have led to improved fat taste sensitivity leading to a decreased intake of fatty foods as observed in the study. “These and previous peer review published findings (Journal of Functional Foods182015 994-1001, and Nutracos May 2015) on the component of the FB3 formula’s C. forskohlii extract, suggest that in conjunction with a hypocaloric diet this compound may be useful in the management of lipid metabolism in healthy overweight and obese individuals. Further this component has been successfully researched  in a proprietary combination that also includes Salacia reticulata andSesamum indicumas part of FB3 (Journal of Functional Foods182015 994-1001, and Nutracos May 2015).”
 
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